Injection Reactions (IR) – Get on with Life

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About OCREVUS
Is OCREVUS right for me?
- RRMS
- PPMS
Understanding MS
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Home
About OCREVUS
Is OCREVUS right for me?
- RRMS
- PPMS
Understanding MS
Resources & Support
FAQs
Contact Us

Some possible symptoms may include redness, pain, swelling, or itchiness at the injection site.

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OCREVUS Safety & Side Effects

Ocrevus Consumer Panel

Ocrevus^®IV (ocrelizumab) 300mg vial, and Ocrevus^® SC (ocrelizumab 920 mg/23 mL solution for subcutaneous injection) are Prescription Medicines used to treat relapsing forms of multiple sclerosis (RMS) and primary progressive multiple sclerosis (PPMS).

Ask your doctor if Ocrevus is right for you.

Ocrevus IV is a funded medicine when given as an infusion into the vein, for patients who meet defined criteria. A prescription charge and doctor’s fees apply.
Ocrevus SC is an unfunded medicine when given as an injection under the skin. Ask your health professional about the cost of the medicine and other fees that may apply.

Use only as directed. If symptoms continue or you have side effects, see your healthcare professional.
For more information about Ocrevus:

• talk to your health professional; or
• visit medsafe.govt.nz for Ocrevus Consumer Medicine Information; or
• visit getonwithlife.co.nz or call Roche on 0800 276 243.

Ocrevus has risks and benefits.

Possible common side effects include: swelling of your face, lips, tongue or throat with difficulty breathing; swelling of other parts of your body; shortness of breath, wheezing or trouble breathing; skin problems including rash, itchiness or hives; feeling sick (nausea); fever, flushing or chills; cough, throat irritation or pain; feeling tired; headache; dizziness or light headedness; fast heartbeat.

Do not use Ocrevus if: you have had an allergic reaction to Ocrevus or any of the ingredients.

Tell your doctor if: you have an infection, or a history of a recurring or long-term infection such as hepatitis B; you are taking or have previously taken medicines which may affect your immune system, such as other medicines for MS you or your child intend to have or have had immunisation with any vaccine; you are allergic to any other medicines or any other substances such as foods, preservatives or dyes; you are pregnant or intend to become pregnant; you are breast feeding or plan to breast feed; if you are taking any other medicines, including any that you have bought without a prescription from a pharmacy, supermarket or health food shop; you notice any signs of an infection such as fever or chills, cold sore, shingles or genital sores; stuffy nose or chest; thick mucus in the nose, throat or chest; persistent cough; difficulty sleeping (insomnia); diarrhoea, vomiting and/or stomach cramps (gastroenteritis); skin infections, sinus infections.

Tell your doctor immediately or go to your nearest Accident and Emergency Centre if you notice any of the following: swelling of your face, lips, tongue or throat with difficulty breathing; swelling of other parts of your body; shortness of breath, wheezing or trouble breathing; local reaction at the injection site (Ocrevus SC only), skin problems including rash, itchiness or hives; feeling sick (nausea); fever, flushing or chills; cough, throat irritation or pain; feeling tired; headache; dizziness or light headedness; fast heartbeat.

Panel dated April 2025. All trademarks mentioned herein are protected by law. Roche Products (New Zealand) Limited, Auckland.

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